Pain

"Potentially injury-causing stimuli (noxious stimuli) are detected by specialized nerves that are found in the skin, muscle and viscera. These damage-sensing neurons, nociceptors, respond to tissue damage and can cause a sensation of pain when they are activated.

Tissue damage is detected by sensory neurons that relay messages to the central nervous system. A torrent of information is emerging about the molecular control of these cells, and is opening exciting new opportunities for pharmaceutical development."
Source

The following is a brief list of resources that may have application for clinicians practicing Manual Medicine.

Neuromatrix Theory of Pain

Man Ther. 2003 Aug;8(3):130-40.
A pain neuromatrix approach to patients with chronic pain.
Adv Psychosom Med. 2004;25:78-88.Neurobiology of pain.
Clin J Pain. 2004 Nov-Dec;20(6):469-76.Evidence, mechanisms, and clinical implications of central hypersensitivity in chronic pain after whiplash injury.
Brain. 1998 Sep;121 ( Pt 9):1603-30.The perception of phantom limbs. The D. O. Hebb lecture.

Ronald Melzack - Papers
J Dent Educ. 2001 Dec;65(12):1378-82.Pain and the neuromatrix in the brain.
Pain Pract. 2005 Jun;5(2):85-94.Evolution of the neuromatrix theory of pain. The Prithvi Raj Lecture: presented at the third World Congress of World Institute of Pain, Barcelona 2004.
Anesthesiology. 2005 Jul;103(1):199-202.The McGill pain questionnaire: from description to measurement.
Pain. 1999 Aug;Suppl 6:S121-6.From the gate to the neuromatrix.
Can J Exp Psychol. 1993 Dec;47(4):615-29.Pain: past, present and future.
Ann N Y Acad Sci. 2001 Mar;933:157-74.Central neuroplasticity and pathological pain.
Patol Fiziol Eksp Ter. 1992 Jul-Aug;(4):52-4.Phantom limb pain.


Sunday, October 19, 2008

October 2008

Spine. 2008 Oct 15;33(22):E843-8.
Education of patients after whiplash injury: is oral advice any better than a pamphlet?
Psychosom Med. 2008 Oct;70(8):890-7.Association of depression and anxiety alone and in combination with chronic musculoskeletal pain in primary care patients.
Pain. 2008 Sep 9.
A randomized trial of behavioral physical therapy interventions for acute and sub-acute low back pain